Novosti
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Year 2009 Vol. 17 No 4
ONCOLOGY
MIKHAILOV I.V., BELYAKOVSKY V.N., LUD A.N., AL-YAHIRI A.K.
LONG-TERM RESULTS OF COMBINED TREATMENT OF LOCALLY ADVANCED RESECTABLE GASTRIC CANCER STAGE IV (T4N1-3M0) WITH POSTOPERATIVE CHEMORADIOTHERAPY
The long-term results of combined treatment of 79 patients with locally advanced resectable gastric cancer IV stage (T4N1–3M0) with the use of extended-combined operations and postoperative chemoradiotherapy (I group) were studied. As a control group we studied the results of treatment of 132 patients who received postoperative chemotherapy (II group) and 117 patients who underwent only surgery (III group). General and recurrence-free 3-year survival in group I composed 38,9% and 20,9%, group II – 22,9% and 3,4%, group III – 24,4% and 10,5%, respectively (p <0,003). The use of postoperative chemoradiotherapy was the most effective for the Borrmann III–IV macroscopic forms of the tumors, low and undifferentiated cancer, with proximal localization, subtotal and total tumor of the stomach. Carry out of the postoperative chemoradiotherapy of locally advanced gastric cancer provides a high degree of local control of the tumor. Local recurrence in patients of group I wasn’t observed, whereas in patients of II and III groups it was detected in 12,2% and 21,2% of cases respectively.
- Estimates of the cancer incidence and mortality in Europe in 2006 / J. Ferlay [et al.] // Ann. Oncol. – 2007. – Vol. 18. – P. 581-582.
- Расширенные лимфаденэктомии при раке желудка: аргументы за и против / В. И. Чиссов [и др.] // Рос. онкол. журнал. – 1999. – № 1. – С. 4-6.
- Рак желудка: что определяет стандарты хирургического лечения / М. И. Давыдов [и др.] // Практич. онкол. – 2001. – № 3 (7). – С. 18-24.
- Хирургическое лечение распространенных форм рака желудка / В. А. Тарасов [и др.] // Практич. онкол. – 2001. – № 3 (7). – С. 52-58.
- Черноусов, А. Ф. Хирургия рака желудка / А. Ф. Черноусов, С. А. Поликарпов, Ф. А. Черноусов. – М.: ИздАТ, 2004. – 560 с.
- Скоропад, В. Ю. Рецидивы рака желудка: закономерности развития, профилактика и лечение / В. Ю. Скоропад, Б. А. Бердов // Рос. онкол. журнал. – 2005. – № 6. – C. 47-52.
- Multi-Institutional Trial of Preoperative Chemoradiotherapy in Patients With Po-tentially Resectable Gastric Carcinoma / J. A. Ajani [et al.] // Journal of clinical oncology. – 2004. – Vol. 22. – N 14. – P. 2774-2780.
- Japanese Classification of Gastric Cancer // Gastric Cancer / Gastric Cancer Association. – 2nd English ed. Japanese. – 1998. – Vol. 1. – P. 10-24.
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