Novosti
Khirurgii

 This journal is
indexed in Scopus
journal cover
android icon Android Applicaion

Year 2011 Vol. 19 No 4

ANESTHESIOLOGY-REANIMATOLOGY

D.V. OSIPENKO, A.V. MAROCHKOV

IMPACT ANALYSIS OF ANESTHESIA MAINTENANCE COMPONENTS WITH APPLICATION OF PROPOFOL OR THIOPENTAL SODIUM IN EARLY OR DISTANT POSTOPERATIVE PERIOD IN PATIENTS WHO UNDERWENT SURGERIES ON CAROTID ARTERIES

Objectives. To study the impact of anesthesia components based on propofol or thiopental sodium on the nearest and distant period of life of the patients who underwent the carotid arteries surgeries.
Methods. Retrospective analysis of the medical cards of patients operated on the carotid arteries is performed. The patients were divided into 2 groups: the first one (91 operated patients) received propofol for anesthesia; the second one (102 operations) got thiopental sodium. The estimation of parameters of anesthesia, surgery, complications, lethality as well as the components of life quality and survival rate after the discharge from the hospital was done.
Results. Thiopental sodium usage was accompanied by higher arterial pressure at such stages of operation as beginning of the operation, clamping of the artery, the end of operation and greater frequency antihypertensive drugs use in comparison with propofol. In the group of patients in whom thiopental sodium was used greater duration of ALV after the operation was registered. During the period of hospitalization no reliable differences between groups were established. 1-4 years after the operation differences in life quality according to EQ-VAS as well as health indexes, survival rate were not established in the groups.
Conclusions. The use of thiopental sodium or propofol to support anesthesia doesn't influence either the complications frequency or the lethality rate during the nearest and distant periods.

Keywords: anesthesia, carotid arteries, propofol, thiopental sodium, postoperative period, complications, life quality, survival rate
p. 89 – 99 of the original issue
References
  1. Рекомендации по ведению больных с ишемическим инсультом и транзиторными ишемическими атаками 2008г. Исполнительный комитет Европейской инсультной организации (ESO) и Авторский комитет ESO [Электронный ресурс] / Ассоциация специалистов нейрореабилитации НЕЙРОРЕАМЕД. – 2009. – Режим доступа: http//www.neuromed.info/index.php?option=com_content&view=article&id=144:-2008&catid=1:latest-news. – Дата доступа: 14.08.2010.
  2. Mackey, W. C. Carotid artery surgery a problem based approach / A. R. Naylor, W. C. Mackey. – London- Edinburgh- New York- Philadelphia –St. Louis -Toronto, 2000. – 607 p.
  3. Howell, S. J. Carotid endarterectomy / S. J. Howell // British Journal of Anaesthesia. – 2007. – N 99. – P. 119-131.
  4. Шмигельский, А. В. Анестезия при каротидной эндартерэктомии / А. В. Шмигельский, А. Ю. Лубнин // Анестезиология и реаниматология. – 2008. – № 2. – С. 45-50.
  5. Защита мозга от ишемии: состояние проблемы / Е. А. Бабаян [и др.] // Анестезиология и реаниматология. – 2005. – № 4. – С. 4-14.
  6. Abelha, F. J. Quality of life after carotid endarterectomy / F. J. Abelha, S. Quevedo, H. Barros // BMC Cardiovascular Disorders. – 2008. – N 8. – P. 58-61.
  7. Post Changes in health-related quality of life after carotid endarterectomy / E. M. Vriens [et al.] // Eur. J. Vasc. Endovasc. Surg. – 1998. – N 16. – P. 395-400.
  8. Improved quality of life among patients with symptomatic carotid artery disease undergoing carotid endarterectomy / A. Dardik [et al.] // J. Vasc. Surg. – 2001. – N 33. – P. 329-333.
  9. User guide Basic information on how to use EQ-5D / A. Dardik [et al.]. – EuroQol Group, 2009. – 24 p.
  10. Kind, P. UK Population Norms for EQ-5D / P. Kind, G. Hardman, S. Macran; Centre for Health Economics University of York, 1999. – 98 p.
Contacts | ©Vitebsk State Medical University, 2007-2023