Year 2014 Vol. 22 No 2

GENERAL AND SPECIAL SURGERY

R.V. SABADOSH

THE ROLE OF SMALL SAPHENOUS VEIN IN THE DEEP VENOUS THROMBOSIS DEVELOPMENT AT ACUTE VARICOSE THROMBOPHLEBITIS OF THE LOWER LIMBS

SHEE “Ivano-Frankovsk National Medical University”,
The Ukraine

Objectives. To improve the treatment results of patients with acute varicose thrombophlebitis (AVTP) of the lower limbs by studying the role of a small saphenous vein (SSV) in the extension of a thrombotic process in the deep venous system.
Methods. 236 patients with AVTP were examined. After the color duplex scanning the limbs were referred to one of 3 groups: the 1st group with thrombosis of the superficial veins; the 2nd – the limbs with thrombotic process in the superficial and perforating veins; and the 3rd – the limbs with thrombotic process in the superficial and deep veins. The thrombosis frequency of SSV and great saphenous vein (GSV) were compared in each of 3 indicated groups as well as inside of the third one.
Results. Among all patients with AVTP, complicated with deep venous thrombosis (DVT), the frequency of GSV thrombosis made up 70.2% (95% CI 55,1-82,7%) and SSV – 34,0% (20,9-49,3%) (p=0,004). Among the same patients but with a pathological reflux in SSV and GSV simultaneously, the frequency of SSV thrombosis composed 88,9% (51,8-99,7%) and GSV – 44,4% (13,7-78,8%) (p=0,007). The frequency of SSV thrombosis in the 2nd group in contrast to the frequency of thrombosis of GSV was higher than in the 1st group, and the difference of thrombosis frequency in groups 3 and 1 was statistically higher than for GSV.
Conclusions. From the obtained results it can be concluded that thrombosis of SSV in case of AVTP plays more important role in the development of accompanying DVT than thrombosis of GSV. However, due to the considerably more frequent detection of pathological reflux in the GSV and its thrombosis among all patients with AVTP complicated DVT is more common.

Keywords: superficial vein thrombosis, varicose veins, small saphenous vein, deep venous thrombosis
p. 184 – 190 of the original issue
References
  1. Wichers IM, Di Nisio M, Buller HR, Middeldorp S.Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review. Haematologica. 2005 May;90(5):672–7.
  2. Quenet S, Laporte S, Decousus H, Leizorovicz A, Epinat M, Mismetti P; Factors predictive of venous thrombotic complications in patients with isolated superficial vein thrombosis. STENOX Group. J Vasc Surg. 2003 Nov;38(5):944–9.
  3. Decousus H, Prandoni P, Mismetti P, Bauersachs RM, Boda Z, Brenner B, Laporte S, Matyas L, Middeldorp S, Sokurenko G, Leizorovicz A. Fondaparinux for the treatment of superficial-vein thrombosis in the legs. CALISTO Study Group. N Engl J Med. 2010 Sep 23;363(13):1222–32.
  4. Ascher E, Hanson JN, Salles-Cunha S, Hingorani A. Lesser saphenous vein thrombophlebitis: its natural history and implications for management. Vasc Endovascular Surg. 2003 Nov-Dec;37(6):421–7.
  5. Rusin V². Anatomotopograf³chn³ osoblivost³ malo¿ p³dshk³rno¿ veni ta vib³r metodu kh³rurg³chnogo l³kuvannia gostrogo varikotrombofleb³tu [Anatomotopographic features of small saphenous vein and the choice of surgical treatment of acute varicose thrombophlebitis ]. Praktichna Meditsina. 2011;(4):10–19.
  6. Chengelis DL, Bendick PJ, Glover JL, Brown OW, Ranval TJ.Progression of superficial venous thrombosis to deep vein thrombosis. J Vasc Surg. 1996 Nov;24(5):745–9.
  7. Verlato F, Zucchetta P, Prandoni P, Camporese G, Marzola MC, Salmistraro G, Bui F, Martini R, Rosso F, Andreozzi GM.An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh. J Vasc Surg. 1999 Dec;30(6):1113–5.
  8. Kirienko AI, Matiushenko AA, Andriiashkin VV, Son DA. Radikal'noe khirurgicheskoe lechenie ostrogo varikotromboflebita [Radical surgical treatment of acute varicose thrombophlebitis]. Grudn i Serd-Sosud Khirurg. 2003;(2):43–46.
  9. Savel'ev VS, Pokrovskii AV, Zatevakhin II, Kirienko AI. Rossiiskie klinicheskie rekomendatsii po diagnostike i lecheniiu khronicheskikh zabolevanii ven [Russian clinical guidelines for the diagnosis and treatment of chronic venous disease]. Flebologiia. 2013;7(2, vyp. 2):2-47.
  10. Decousus H, Quere I, Presles E, Becker F, Barrellier MT, Chanut M, Gillet JL, Guenneguez H, Leandri C, Mismetti P, Pichot O, Leizorovicz A. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med. 2010 Feb 16;152(4):218-24.
  11. Chernukha LM, Shchuk³n SP. Trombotichn³ uskladnennia vazhkikh form varikozno¿ khvorobi: d³agnostika, kh³rurg³chne l³kuvannia ta prof³laktika trombembol³¿ legenevo¿ arter³¿ [Thrombotic complications of severe varicose disease: diagnosis, surgical treatment and prevention of pulmonary embolism in patients with thromboembolism]. Nauk V³sn Uzhgor Un-t Cer Meditsina. 2012;3(45):128–32.
  12. Guch AA, Chernukha LN. Varikoznaia bolezn'. Klassifikatsiia, ul'trazvukovaia d³agnostika [Varicose veins. Classification, ultrasound diagnostics]. Kl³n Kh³rurg³ia. 2004;(3):46–51.
Address for correspondence:
76000, Ukraina, g. Ivano-Frankovsk, ul. Galitskaia, d. 2, GVUZ «Ivano-Frankovskii natsional'nyi meditsinskii universitet», kafedra khirurgii stomatologicheskogo fakul'te-ta.
e-mail: r.sabadosh@gmail.com
Sabadosh Rostislav Vasil'evich
Information about the authors:
Sabadosh R.V. PhD, an associate professor of the surgery chair of the dental faculty of SHEE “Ivano-Frankovsk National Medical University”.
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