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Year 2010 Vol. 18 No 5
MORKHAT V.I., VOLKOVICH T.K.
FEATURES OF PRIMARY AND SECONDARY FORMS OF BACTERIAL KERATITIS COURSE
Objectives. To study the features of primary and secondary forms of bacterial keratitis (BK).
Methods. The investigation was performed on 106 patients with bacterial keratitis. The first group was composed by 43 patients with the primary form of the disease, the second – by 63 patients with the secondary form. Microbiological investigation with sensitivity definition to antibacterial preparations was done in 58 cases. The analysis of reparative abilities with calculation of corneal epithelialization factor was carried out in 44 patients.
Results. Secondary form of bacterial keratitis developed more often (р=0,04) in persons older those at able-bodied age. Primary form of bacterial keratitis developed more often in males of able-bodied age. The conditional-pathogenic microflora prevailed in both groups.
Conclusions. St. Epidermidis prevails in etiology of primary and secondary forms of bacterial keratitis development which sensitivity is most marked to an antibacterial preparation tobramycin.
The primary form of bacterial keratitis is characterized by the marked reparative processes in the regress and scarring stage, secondary – by low intensity of reparative processes in all stages of inflammatory process resulting in prolongation of the ulcer-inflammatory defect epithelialization.
- Bacterial keratitis: predisposing factors, clinical and microbiological review of 300 cases / T. Bourcier [et al.] // Br. J. Ophthalmol. – 2003. – Vol. 87. – P. 834-838.
- Clinical outcomes of keratitis / M. D. Green [et al.] // Clin. and Exper. Ophthalmol. – 2007. – Vol. 35. – P. 421-426.
- Khurana, A. K. Ophthalmology / A. K. Khurana. – New age international, 2007. – 603 p.
- The efficacy and safety of topical polymyxin B, neomycin and gramicidin for treatment of presumed bacterial corneal ulceration / M. I. Bosscha [et al.] // Br. J. Ophthalmol. – 2004. – Vol. 88. – P. 25-28.
- Severe infective keratitis leading to hospital admission in New Zealand / T. Wong [et al.] // Br. J. Ophthalmol. – 2003. – Vol. 87. – P. 1103-1108.
- Trends in resistance to ciprofloxacin, cefazolin, and gentamicin in the treatment of bacterial keratitis / N. A. Afshari [et al.] // Journal of ocular pharmacology and therapeutics. – 2008. – Vol. 24. – P. 217-223.
- Шаимова, В. А. Клинико-этиологические особенности различных типов течения гнойной язвы роговицы / В. А. Шаимова // Вестн. офтальмологии. – 2002. – № 1. – С. 39-41.
- Волкович, Т. К. Импрессионная цитология в диагностике бактериального кератита / Т. К. Волкович, Т. А. Имшенецкая, И. В. Самсонова // ARS MEDICA. Новое в офтальмологии. – 2009. – № 9. – С. 32-37.