Novosti
Khirurgii
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indexed in Scopus



Year 2012 Vol. 20 No 1

GENERAL AND SPECIAL SURGERY

V.I. PETUKHOV, V.P. BULAVKIN, V.K. OKULICH, F.V. PLOTNIKOV

RATIONAL USE OF ANTIBIOTICS IN POSTTRAUMATIC OSTEOMYELITIS TREATMENT CONSIDERING DYNAMICS OF RESISTANCE CHANGE

EE Vitebsk State Medical University,
the Republic of Belarus

Objectives. To evaluate antibiotics sensitivity of pathogens obtained from the patients with the posttraumatic osteomyelitis and to work out recommendations concerning rational antibiotics therapy.
Methods. 191 patients with the posttraumatic osteomyelitis were examined using the biological method. Microorganisms identification was carried out by means of the test-systems on the biochemical analyzer ATB Expression. Evaluation of the microorganisms sensitivity to the antibacterial preparation was carried out on the biochemical analyzer ATB Expression as well as using original test-systems AB-STAPH, AB-PSEU, AB-GRAM(-) and AB-ENTER.
Results. Equal ratio of gram-positive and gram-negative floras during the whole period of patients hospitalization was determined. Pseudomonas aeruginosa was reliably more frequently observed in the quaternary inoculations compared with the primary ones. Reliable growth of microorganisms resistance to antibacterial preparations is registered.
Conclusions. Use of the developed scheme of the rational empirical antibiotics therapy in the complex treatment of posttraumatic osteomyelitis permitted to shorten hospitalization terms from 382,7 to 21,12,3 days (p<0,05).

Keywords: osteomyelitis, antibiotic, antibiotics resistance
p. 71 79 of the original issue
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Address for correspondence:
210023, Respublika Belarus', g. Vitebsk, pr. Frunze, d. 27, UO Vitebskii gosudarstvennyi meditsinskii universitet, kafedra khirurgii FPK i PK.
e-mail: dr.plotnikov@mail.ru,
Plotnikov Filipp Viktorovich
Information about the authors:
Petukhov V.I. Doctor of medical sciences, Associate Professor, head of the chair of surgery of the faculty of advanced training and retraining of specialists of EE Vitebsk State Medical University.
Bulavkin V.P. Candidate of medical sciences, associate professor of the chair of surgery of the faculty of advanced training and retraining of specialists of EE Vitebsk State Medical University.
Okulich V.K. Candidate of medical sciences, associate professor of the chair of clinical microbiology of EE Vitebsk State Medical University.
Plotnikov F.V. Master of medical sciences, post-graduate student of the chair of surgery of the faculty of advanced training and retraining of specialists of EE Vitebsk State Medical University.
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