Novosti
Khirurgii
This journal is
indexed in Scopus



Year 2013 Vol. 21 No 4

GENERAL AND SPECIAL SURGERY

DOI: http://dx.doi.org/10.18484/2305-0047.2013.4.78   |  

A.G. SALMANOV 1, V.F. MARIEVSKY2

ANTIBIOTIC RESISTANCE OF NOSOCOMIAL STRAINS OF STAPHYLOCOCCUS AUREUS IN THE UKRAINE: THE RESULTS OF MULTICENTER STUDY

State Sanitary and Epidemiological Department of the Ukraine1
SE Institute of Epidemiology and Infectious Diseases named after L.V.Gromashevsky of National Academy of Medical Siences of the Ukraine2, Kiev,
The Ukraine

Objectives. To study the activity of antimicrobials against clinical strains of S.aureus isolated in the surgical hospitals of different regions of the Ukraine.
Methods. The clinical strains of S.aureus (119041) isolated in 2008-2012 yrs in 97 surgical hospitals of 27 regions of the Ukraine have been studied. Clinical isolates were allocated and identified in 83 microbiological laboratories included in the research of medical establishments. The material for the epidemiological study was the data of the laboratory journals of the examined surgical hospitals of the Ukraine. S.aureus susceptibility to 37 antibiotics was investigated by the disc-diffusion test in accordance with the recommendations of the National Committee for Clinical laboratory Standards (NCCLS).
Results. The highest activity to S.aureus had linezolid, imipenem, vancomycin, meropenem, ceftriaxone, ciprofloxacin, netilmicin, gatifloxacin, and cefotaximum. The high rates of resistance were registered for penicillin (48,3%), ampicillin (41,2%), tetracycline (40,1%), ampicillin/sulbactam (35,2%), and to lincomycin (34,5%). The frequency of isolation of MRSA among tested strains was 33,8% varying from 20,7% to 55,8% in surgical hospitals of different regions.
Conclusions. Antibiotic resistance to S.aureus in surgical hospitals, being a subject of the research is considered to be a serious therapeutic and epidemiologic problem. Taking into account the constant changes and significant differences of the S.aureus resistance levels observed in various regions, the constant monitoring of antibiotic resistance to antimicrobials in every in-patient medical institution is required and on the base of the local obtained results to elaborate the hospital record sheets. Antibiotics application tactics should be determined in accordance with the local data of resistance to them in each surgical in-patient institution. The system of epidemiologic surveillance over microbial resistance should be established on the local, regional, and national levels.

Keywords: Staphylococcus aureus, antimicrobial resistance, surgery, nosocomial infections, MRSA
p. 78 83 of the original issue
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Address for correspondence:
01601, Ukraina, g. Kiev, ul. Grushevskogo, d. 7, Gosudarstvennaia sanitarno-epidemiologicheskaia sluzhba Ukrainy,
e-mail: moz.sag@bigmir.net,
Salmanov Aidyn Gurbanovich
Information about the authors:
Salmanov A.G. PhD, a chief specialist of State Sanitary and Epidemiological Department of the Ukraine.
Marievsky V.F. MD, professor, a head of laboratory of disinfectology of SE Institute of Epidemiology and Infectious Diseases named after L.V.Gromashevsky of NAMS of the Ukraine.
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