Novosti
Khirurgii
This journal is
indexed in Scopus



Year 2016 Vol. 24 No 4

GENERAL & SPECIAL SURGERY

DOI: http://dx.doi.org/10.18484/2305-0047.2016.4.368   |  

Y.S. VINNIK, S.S. DUNAEVSKAYA, D.A. ANTUFRIEVA

LIFE QUALITY STUDY OF PATIENTS WITH OBLITERATING ATHEROSCLEROSIS OF THE VESSELS IN THE LOWER EXTREMITIES

SBEE HPE "Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky",
Krasnoyarsk
The Russian Federation

Objectives. To estimate life quality of patients with obliterating atherosclerosis of the vessels in the lower extremities against the background of a combined application of lyophilisate alprostadil and a systemic ozone therapy.
Methods. The patients were distributed among four groups depending on the conducted therapy. The standard treatment regimen was applied in the control group. The lyophilisate alprostadil was included in the complex therapy for patients of the first group. The systemic ozone therapy together with a basic therapy was applied in the second group. The lyophilisate alprostadil and ozone therapy were included in the complex treatment regimen for patients of the third group. To study the life quality of patients the questionnaire SF-36 was used before and after a therapy (6 months afterwards).
Results. Low rates of physical functioning and role-physical functioning as well as pain intensiveness were found out to be present in patients with atherosclerosis on admission. Low rates in all groups testified the pain considerably limits the activity of the studied patients. General health, vitality level, social and role-physical functioning were evaluated as average ones. Thus, the indices in all groups had no significant differences and were comparable. Six months afterwards, the indices of "physical functioning" for patients treated with lyophilisate alprostadil and ozone therapy together with the complex treatment regimen were higher than in the control, first and second groups. In 6 months the reduction of "a health psychological component" caused by progression of the main disease was noted in the control group.
Conclusion. The conducted study has verified that a combined application of lyophilisate alprostadil and a systemic ozone therapy reliably reduces pain during walking, thus improving physical and emotional health of patients.

Keywords: obliterating atherosclerosis of lower limbs vessels, physical functioning, role-physical functioning, complex therapy, life quality, lyophilisate alprostadil, ozone therapy
p. 368-372 of the original issue
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Address for correspondence:
660077, Russian Federation, Krasnoyarsk, Partizan Zheleznyak, 1, Medical University "Krasnoyarsk State Medical University named by Professor VF Voyno-Yasenetsky ", chair of general surgery named by Professor MI Gulman.
Tel: 963-191-29-70
E-mail: Vikto-potapenk@yandex.ru
Information about the authors:
Vinnik Y.S. MD, Professor, Head, SBEE HPE "Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky", chair of general surgery named after Professor M.I. Gulman.
Dunaevskaya S.S. MD, Ass. Professor, SBEE HPE "Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky", Professor, chair of general surgery named after Professor M.I. Gulman.
Antufrieva D.A. Post-graduate student, SBEE HPE "Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky", chair of general surgery named after Professor M.I. Gulman.
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