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2013 г. №1 Том 21

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DOI: http://dx.doi.org/10.18484/2305-0047.2013.1.105   |  

И.И. ПИКИРЕHЯ 1, Ш.З. ШАРИПОВ 1, О.С. БОГУШЕВИЧ 2

БИЛИАРHЫЕ СТРИКТУРЫ ПОСЛЕ ОРТОТОПИЧЕСКОЙ ТРАHСПЛАHТАЦИИ ПЕЧЕHИ

ГУО «Белорусская медицинская академия последипломного образования» 1,
Комитет по здравоохранению Мингорисполкома 2, г. Минск,
Республика Беларусь

В статье представлен обзор исследований, посвященных изучению факторов риска развития билиарных осложнений после трансплантации печени. Анализ литературы показал, что, несмотря на значительные достижения трансплантации печени в лечении пациентов с терминальной стадией ее поражения, обусловленной циррозом и рядом очаговых заболеваний, все еще остается высокая частота развития билиарных осложнений в посттрансплантационном периоде.
Наиболее распространенными видами билиарных осложнений, развивающихся после ортотопической трансплантации, являются: несостоятельность билиарного и билиодигистивного анастомозов, их стриктура, а также неанастомотические стриктуры желчных протоков. Среди множества факторов, влияющих на развитие билиарных осложнений в посттрансплантационном периоде, основными являются: длительная холодовая ишемия трансплантата, нарушение кровообращения желчных протоков, технические проблемы.
Обобщая данные литературы, факторы риска неанастомотических стриктур можно разделить на три основные группы: ишемические, иммунологические и индуцированные солями желчных кислот.
Наличие множества факторов риска развития билиарных осложнений требует дальнейшего изучения их и разработки методов предупреждения развития билиарных осложнений после ортотопической трансплантации печени.

Ключевые слова: ортотопическая трансплантация печени, билиарные осложнения, неанастомотические билиарные стриктуры
с. 105 – 110 оригинального издания
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Адрес для корреспонденции:
210013, Республика Беларусь, г. Минск, ул. П. Бровки, д. 3, кор. 3, ГУО «Белорусская медицинская академия последипломного образования», кафедра кардиохирургии с курсом трансплантологии,
e-mail: pik-med@tut.by,
Пикиреня Иван Иванович
Cведения об авторах:
Пикиреня И.И., к.м.н., заведующий кафедрой трансплантологии ГУО «Белорусская медицинская академия последипломного образования».
Шарипов Ш.З., аспирант кафедры кардиохирургии с курсом трансплантологии ГУО «Белорусская медицинская академия последипломного образования».
Богушевич О.С., к.м.н., главный хирург Комитета здравоохранения Мингорисполкома.
Контакты | ©Витебский государственный медицинский университет, 2007