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Year 2011 Vol. 19 No 5




Today study of development dynamics and course of acute thrombosis of deep veins (TDV) in experiment, randomized comparisons of thrombolysis and thrombectomy with anticoagulant therapy proves the thesis that treatment strategy aimed to remove thrombus decreases the marked character of post thrombotic changes. The literature review with justification of the role and place of catheter thrombolysis in TDV treatment is presented in the article. It is proved that early thrombus removal from the main veins permits not only to decrease significantly the risk of post thrombotic disease (PTD) development but also to improve the life quality of patients.

Keywords: venous thrombosis, thrombolysis, thrombectomy
p. 128 - 137 of the original issue
  1. Comerota, A. J. Treatment of acute iliofemoral deep venous thrombosis: a strategy of thrombus removal / A. J. Comerota, D. Paolini // Eur. J. Vasc. Endovasc. Surg. 2007. Vol. 3. P. 351-360.
  2. Delis, K. T. Venous claudication in iliofemoral thrombosis: long-term effects on venous hemodynamics, clinical status, and quality of life / K. T. Delis, D. Bountouroglou, A. O. Mansfield // Ann. Surg. 2004. Vol. 239, N 1. P. 118-126.
  3. Venous function assessed during a 5 year period after acute ilio-femoral venous thrombosis treated with anticoagulation / H. Akesson [et al.] // Eur. J. Vasc. Surg. 1990. Vol. 4, N l. P. 43-48.
  4. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy / H. R. Buller [et al.] // Chest. 2004. Vol. 126. Suppl. 3. P. 401S-28S.
  5. Elsharawy, M. Early results of thrombolysis vs anticoagulation in iliofemoral venous thrombosis. A randomised clinical trial / M. Elsharawy, E. Elzayat // Eur. J. Vasc. Endovas. Surg. 2002. Vol. 24, N 3. P. 209-214.
  6. Catheter- directed thrombolysis and/or thrombectomy with selective endovascular stenting as alternatives to systemic anticoagulation for treatment of acute deep vein thrombosis / L. S. Jackson [et al.] // Am. J. Surg. 2005. Vol. 190. P. 864-688.
  7. Tissue plasminogen activator (rt-PA) vs heparin in deep vein thrombosis. Results of a randomized trial / A. G. Turpie [et al.] // Chest. 1990. Vol. 97. Suppl. 4. P. 172S-175S.
  8. Controlled multicenter pilot study of urokinase- heparin and streptokinase in deep vein thrombosis / J. C. van de Loo [et al.] // Thromb. Haemost. 1983. Vol. 50. P. 660-663.
  9. Watz, R, Rapid thrombolysis and preservation of valvular venous function in high deep vein thrombosis. A comparative study between streptokinase and heparin therapy / R. Watz, G. F. Savidge // Acta Med. Scand. 1979. Vol. 205, N 4. P. 293-298.
  10. Venous function assessed during a 5 year period after acute ilio-femoral venous thrombosis treated with anticoagulation / H. Akesson [et al.] // Eur. J. Vasc. Surg. 1990. Vol. 4, N l. P. 43-48.
  11. Streptokinase treatment of deep venous thrombosis / U. Albrechtsson [et al.] and the postthrombotic syndrome. Follow-up evaluation of venous function // Arch. Surg. 1981. Vol. 16, N 1. P. 33-37.
  12. Kakkar, W. Hemodynamic and clinical assessment after therapy for acute deep vein thrombosis. A prospective study / W. Kakkar, D. Lawrence // Am. J. Surg. 1985. Vol. 150, N 4 A. P. 54-63.
  13. Valvular reflux after deep vein thrombosis: incidence and time of occurrence / A. Markel [et al.] // J. Vasc. Surg. 1992. Vol. 1, N 5. P. 377-382.
  14. The socioeconomic effects of an iliofemoral venous thrombosis / T. F. ODonnell [et al.] // J. Surg. Res. 1977. Vol. 22. P. 483-488.
  15. The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based Guidelines // Chest. 2004. Vol. 126. Suppl. 3.
  16. Antithrombotic and Thrombolytic Therapy, ACCP Guidelines // Chest. 8th ed. 2008. Vol. 133. Suppl. 6.
  17. , // . 2010. . . 4. . 2. 1.
  18. Relationship between changes in the deep venous system and the development of the post-thrombotic syndrome after an acute episode of lower limb deep vein thrombosis: a one- to six-year follow-up / B. F. Johnson [et al.] // J. Vasc. Surg. 1995. Vol. 21. P. 307-312.
  19. Significance of popliteal reflux in relation to ambulatory venous pressure and ulceration / K. C. Shull [et al.] // Arch. Surg. 1979. Vol. 114. P. 1304-1306.
  20. Treatment of deep vein thrombosis with streptokinase / F. Duckert [et al.] // BMJ. 1975. Vol. 1. P. 479-481.
  21. Grunwald, M. R. Comparison of urokinase, alteplase, and reteplase for catheter-directed thrombolysis of deep venous thrombosis / M. R. Grunwald, L. V. Hofmann // J. Vasc. Interv. Radiol. 2004. Vol. 15. P. 347-352.
  22. Controlled study of thrombolytic therapy in deep vein thrombosis / M. J. Tsapogas [et al.] // Surgery. 1973. Vol. 74. P. 973-984.
  23. Effects of thrombolysis and venous thrombectomy on valvular competence, thrombogenicity, venous wall morphology, and function / J. S. Cho [et al.] // J. Vasc. Surg. 1998. Vol. 28. P. 787-799.
  24. Thrombolysis for experimental deep venous thrombosis maintains valvular competence and vasoreactivity / J. M. Rhodes [et al.] // J. Vasc. Surg. 2000. Vol. 31. P. 1193-1205.
  25. Spontaneous lysis of deep venous thrombi: rate and outcome / L. A. Killewich [et al.] // J. Vasc. Surg. 1989. Vol. 9, N 1. P. 89-97.
  26. Deep venous insufficiency: the relationship between lysis and subsequent reflux / M. H. Meissner [et al.] // J. Vasc. Surg. 1993. Vol. 18. P. 596-605.
  27. A prospective study of streptokinase and heparin in the treatment of deep vein thrombosis / H. Arnesen [et al.] // Acta Med. Scand. 1978. Vol. 203. P. 457-463.
  28. Browse, N. L. Streptokinase and deep vein thrombosis / N. L. Browse, M. L. Thomas, H. P. Pirn // BMJ. 1968. Vol. 3. P. 717-720.
  29. A comparative randomized trial of heparin versus streptokinase in the treatment of acute proximal venous thrombosis: an interim report of a prospective trial / M. S. Elliot [et al.] // Br. J. Surg. 1979. Vol. 66. P. 838-843.
  30. Randomized controlled trial of tissue plasminogen activator in proximal deep venous thrombosis / S. Z. Goldhaber [et al.] // Am. J. Med. 1990. Vol. 88, N 3. P. 235-240.
  31. Jeffery, P. Treatment of deep vein thrombosis with heparin or streptokinase: long-term venous function assessment / P. Jeffery, E. J. Immelman, J. Amoore // Proc. Sec. Int. Vasc. Symp. London, 1986.
  32. Treatment of deep vein thrombosis. A trial of heparin, streptokinase, and arvin / W. Kakkar [et al.] // BMJ. 1969. Vol. 1. P. 806-810.
  33. Quantitative venographic assessment of deep vein thrombosis in the evaluation of streptokinase and heparin therapy / V. J. Marder [et al.] // J. Lab. Clin. Med. 1977. Vol. 89. P. 1018-1029.
  34. Comparison of heparin and streptokinase in the treatment of venous thrombosis / J. M. Porter [et al.] // Am. Surg. 1975. Vol. 41. P. 511-519.
  35. Robertson, B. R. Value of streptokinase and heparin in treatment of acute deep venous thrombosis. A coded investigation / B. R. Robertson, I. M. Nilsson, G. Nylander // Acta Chir. Scand. 1968. Vol. 134, N 3. P. 203-208.
  36. Healing of deep venous thrombosis: venographic findings in a randomized study comparing streptokinase and heparin / J. Rosch [et al.] // Am. J. Roentgenol. 1976. Vol. 127. P. 553-558.
  37. Deep vein thrombosis treated with streptokinase or heparin. A randomized study / A. J. Seaman [et al.] // Angiology. 1976. Vol. 27. P. 549-556.
  38. Long-term sequelae of calf vein thrombosis treated with heparin or low-dose streptokinase / S. Schulman [et al.] // Acta Med. Scand. 1986. Vol. 219. P. 349-357.
  39. Arnesen, H. Streptokinase of heparin in the treatment of deep vein thrombosis. Follow-up results of a prospective study / H. Arnesen, A. Hoiseth, B. Ly // Acta Med. Scand. 1982. Vol. 211, N 1-2. P. 65-68.
  40. Alkjaersig, N. The mechanism of clot dissolution by plasmin / N. Alkjaersig, A. P. Fletcher, S. Sherry // J. Clin. Invest. 1959. Vol. 38. P. 1086-1095.
  41. Iliofemoral deep vein thrombosis: conventional therapy versus lysis and percutaneous transluminal angioplasty and stenting / A. F. AbuRahma [et al.] // Ann. Surg. 2001. Vol. 233. P. 752-760.
  42. Catheter-directed thrombolysis for iliofemoral deep venous thrombosis improves health-related quality of life / A. J. Comerota [et al.] // J. Vasc. Surg. 2000. Vol. 32, N 1. P. 130-137.
  43. Intraclot recombinant tissue plasminogen activator in the treatment of deep venous thrombosis of the lower and upper extremities / M. K. Home [et al.] // Am. J. Med. 2000. Vol. 108, N 3. P. 251-255.
  44. Kasirajan, K. Percutaneous AngioJet thrombectomy in the management of extensive deep venous thrombosis / K. Kasirajan, B. Gray, K. Ouriel // J. Vasc. Interv. Radiol. 2001. Vol. 12, N 2. P. 179-185.
  45. Adjunctive percutaneous mechanical thrombectomy for lower-extremity deep vein thrombosis: clinical and economic outcomes / H. S. Kim [et al.] // J. Vasc. Interv. Radiol. 2006. Vol. 17. P. 1099-1104.
  46. Preservation of venous valve function after catheter-directed and systemic thrombolysis for deep venous thrombosis / M. K. Laiho [et al.] // Eur. J. Vasc. Endovasc. Surg. 2004. Vol. 28. P. 391-396.
  47. Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis / P. H. Lin [et al.] // Am. J. Surg. 2006. Vol. 192. P. 782-788.
  48. Intermittent pneumatic compression of the foot and calf improves the outcome of catheter-directed thrombolysis using low-dose urokinase in patients with acute proximal venous thrombosis of the leg / T. Ogawa [et al.] // J. Vasc. Surg. 2005. Vol. 42. P. 940-944.
  49. Semba, C. P. Catheter-directed thrombolysis for iliofemoral venous thrombosis / C. P. Semba, M. D. Dake // Semin. Vasc. Surg. 1996. Vol. 9, N 1. P. 26-33.
  50. Lower extremity venous thrombolysis with adjunctive mechanical thrombectomy / S. Vedantham [et al.] // J. Vasc. Interv. Radiol. 2002. Vol. 13. P. 1001-1008.
  51. Iliofemoral deep venous thrombosis: safety and efficacy outcome during 5 years of catheter-directed thrombolytic therapy / H. Bjarnason [et al.] // J. Vas. Interv. Radiol. 1997. Vol. 8. P. 405-418.
  52. Comerota, A. J. Catheter-directed thrombolysis for the treatment of acute iliofemoral deep venous thrombosis / A. J. Comerota, S. A. Kagan // Phlebology. 2000. Vol. 15. P. 149-155.
  53. Catheter- directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry / M. W. Mewissen [et al.] // Radiology. 1999. Vol. 211, N 1. P. 39-49.
  54. Meissner, M. H. Early outcome after catheter directed thrombolysis for acute deep venous thrombosis: follow-up of a national multicenter registry / M. H. Meissner, M. Mewissen // J. Vasc. Surg. 2008 (inpress).
  55. Catheter-directed thrombolysis in deep venous thrombosis with use of reteplase: immediate results and complications from a pilot study / F. Castaneda [et al.] // J. Vasc. Interv. Radiol. 2002. Vol. 13. P. 577-580.
  56. Daily catheter-directed single dosing of t-PA in treatment of acute deep venous thrombosis of the lower extremity / R. Chang [et al.] // J. Vasc. Interv. Radiol. 2001. Vol. 12, N 2. P. 247-252.
  57. Safety and efficacy of limited-dose tissue plasminogen activator in acute vascular occlusion / C. K. Shortell [et al.] // J. Vasc. Surg. 2001. Vol. 34. P. 854-859.
  58. Catheter-directed thrombolysis for treatment of ilio-femoral deep venous thrombosis is durable, preserves venous valve function and may prevent chronic venous insufficiency / H. Sillesen [et al.] // Eur. J. Vasc. Endovasc. Surg. 2005. Vol. 30. P. 556-562.
  59. Short- and long-term results after thrombolytic treatment of deep venous thrombosis / J. Schweizer [et al.] // J. Am. Coll. Cardiol. 2000. Vol. 36. P. 1336-1343.
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