Year 2013 Vol. 21 No 2




FSBE SII of Experimental Medicine of the North-west district of RAMS1,
Saint-Petersburg Institute of Bioregulation and Gerontology of the North-west district of RAMS 2,
Clinic Medalp 3,
Railway clinical hospital of JSC Russian railways 4, Saint-Petersburg
The Russian Federation

Objectives. To work out the prognostic models of results at endovenous laser ablation (EVLA) to treat varicose veins according to the combined ultimate point taking into account the patients age on the basis of clinical data of the retrospective cohort multicentre study (RCMS).
Methods. The research was conducted using the data of the retrospective linear cohort multicentre study on the basis of the vascular departments of three specialized clinics of Saint-Petersburg during the period from January, 2010 up to May, 2011. 257 patients with varicose veins of 2 3 classes of clinical manifestation according to were included in the study. The patients were subdivided into 2 cohorts: laser with the wave length of 970 nm was applied in the H cohort; 1470 nm and 1560 nm in W cohort. The evaluation was done according to the combined ultimate point including three components: pain, ecchymosis, the presence of recanalization of the great saphenous vein (GSV) in the middle third of the thigh. The results were divided into 4 groups: the best, good, bad and the worst one. Mathematical-statistic packet of the applied programs KNIME (The Konstanz Information Miner), KNIME Desktop, version 2. 6.0 was used for calculations.
Results. The model of the results prediction of EVLA for different age groups was designed according to general selection and in case of lasers H and W application.
Conclusions. At W-laser application better results of EVLA are predicted in elderly and senile patients than in young patients. In case of H-laser application the result doesnt depend on the age. Range of the linear endovenous energy density (LEED) and the diameter of veins influencing the treatment results are wider for W-laser than for H-laser in all age groups. Maximal difference of EVLA H- and W-lasers results regardless of age were revealed in the range of the vein diameters of 8-10 mm that are seen in greater frequency of obtaining the best results at W-laser application.

Keywords: primary varicose veins, endovenous laser ablation, H-laser, W-laser, prediction of resultss
p. 61 68 of the original issue
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Address for correspondence:
197376, Rossiiskaia Federatsiia, g. Sankt-Peterburg, ul. Akademika Pavlova, d. 12, FGBU NII Eksperimental'noi Meditsiny SZO RAMN,,
Bulatov Vasilii Leonidovich
Information about the authors:
Shaydakov E.V. MD, professor, deputy director of FSBE SII of Experimental Medicine of North-West District of RAMS, Saint-Petersburg.
Bulatov V.L. A researcher of the biogerontology laboratory of the Institute of bioregulation and gerontology of North-West District of RAMS, Saint-Petersburg.
Ilyukhin E.A. Chief physician of the clinic Medalp, Saint-Petersburg.
Sonkin I.N. PhD, a head of the vascular department of the railway clinical hospital JSC Russian railways, Saint-Petersburg.
Grigoryan A.G. Vascular surgeon of FSBE SII of Experimental Medicine of North-West District of RAMS, Saint-Petersburg.
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