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Khirurgii

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Year 2019 Vol. 27 No 3

REVIEWS

O.A. NAZARCHUK 1, M.O. FAUSTOVA 2, S.A. KOLODII 1

MICROBIOLOGICAL CHARACTERISTICS OF INFECTIOUS COMPLICATIONS, ACTUAL ASPECTS OF THEIR PREVENTION AND TREATMENT IN SURGICAL PATIENTS

National Pirogov Memorial Medical University 1, Vinnitsa,
Ukrainian Medical Stomatological Academy 2, Poltava,
Ukraine

According to the literature data, microbiota of complications in surgical hospitals consists mainly of representatives of Staphylococcus spp., Enterococcus spp., Escherichia spp., Enterobacter spp., Klebsiella spp., and Pseudomonas spp. However, the spectrum of microorganisms differs depending on the location of the lesions, therapy tactics and the type of unit, where a patient is treated. Nowadays the rapid acquisition of resistance to chemotherapeutic agents by pathogens is becoming the most ambitious problem of modern medicine. In hospitals and intensive care units, the situation is aggravated by the emergence of multi-resistant hospital strains of microorganisms. The mechanisms of bacterial resistance to antibiotics are diverse and can be carried out both at the genetic and at the biochemical level.
The incidence of infectious and inflammatory postoperative complications and increase of the problem of antibiotic resistance among microorganisms dictate the need for careful monitoring of the epidemic situation in hospitals and studying the changing tendencies in the spectrum of dominant pathogens. Moreover, developing and introducing into the clinic of new antibiotics and drugs with antimicrobial activity, revision of existing algorithms for the treatment and prevention of complications arising on the background of surgical interventions are necessary.

Keywords: anti-bacterial agents, antibiotic-resistance, infectious-inflammatory, nosocomial, postoperative complications, surgical infection
p. 318-327 of the original issue
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Address for correspondence:
21018, Ukraine,
Vinnitsa, Pirogov Str., 56,
National Pirogov Memorial Medical University,
Microbiology Department,
Tel. +38 097 729-37-61,
e-mail: nazarchukoa@gmail.com,
Oleksandr A. Nazarchuk
Information about the authors:
Nazarchuk Oleksandr A., PhD, Associate Professor of the Microbiology Department, National Pirogov Memorial Medical University, Vinnitsa, Ukraine.
https://orcid.org/0000-0001-7581-0938
Faustova Mariia O., PhD, Lecturer of the Department of Microbiology, Virology and Immunology, Ukrainian Medical Stomatological Academy, Poltava, Ukraine.
https://orcid.org/0000-0001-5327-6324
Kolodii Svetlana A., PhD, Associate Professor of the Microbiology Department, National Pirogov Memorial Medical University, Vinnitsa, Ukraine.
https://orcid.org/0000-0001-7511-8108
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