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Year 2006 Vol. 14 No 2
A.V. BOGDANOVICH, V.N. SHILENOK, L.N. KIRPICHENOK
PROTEOLYTIC ACTIVITY IN THE BLOOD SERUM AND SMALL INTESTINE IN PATIENTS WITH ACUTE COMISSURAL ILEUS
The analysis of the treatment results of 37 patients with acute commissural ileus is presented in the article. The operation on the commissural dissection was performed in 30 patients; the commissural dissection and resection of the small intestine region was carried out in 7 patients. The nasogastrointestinal intubation with prolonged decompression of the small intestine was included in the treatment complex in all the patients. The intestinal content evacuation and the small intestine irrigation with the physiological solution of sodium chloride were done during the operation and in the postoperative period. The proteolytic activity was studied in the blood serum and the aspirated intestinal content in dynamics. The highest level of proteolytic activity was registered in the 1st and 2nd days of the postoperative period, thus there wasn’t a significant increase of inhibitor activity. It was found out that decrease of proteolytic activity permitted to speak about positive dynamics in the disease course. The investigation results let evaluate the degree of endotoxicosis and therapeutic actions efficacy.
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