Novosti
Khirurgii
This journal is
indexed in Scopus







Year 2006 Vol. 14 No 2

M.A. KRISHTOPOVA, V.S. KUNITSKY, O.D. MYADELETS

EXPERIMENTAL-MORPHOLOGICAL GROUNDING OF POLYETHER COMPLEX FIBERS IMPLANT USE IN SEPTOPLASTY

To ground the application possibilities of the cloth gauze implant to restore the osteal-cartilage framework of the nasal septum after its correction because of curvature we used cloth gauze implant from polyether fibers for the nasal septum plasty in the experimental research on the laboratory animals (rabbits of the chinchilla breed). The open rhinoseptoplasty technique was used to operate on 18 animals. The animals were excluded from the experiment – 3 rabbits every 3, 7, 15, 30, 60 and 120 days after the operation. Histological cuts were stained with hematoxiline-eozine and azan. The following indexes were evaluated: the state of animals (everyday during 4 months), their behavior (active, passive, depressed); the control over the operation wound took place, the character of nasal discharging was evaluated; visual control over the mucous nasal membrane was performed as well as visual estimation of the dissected septum fragment (in the 1, 7, 15, 30, 60 and 120 days after the operation); morphological changes of implants and surrounding tissues of the nasal septum ((in the 1, 7, 15, 30, 60 and 120 days after the operation) were registered. The research results showed that the polyether complex fibers cloth gauze implant suppresses the development of the inflammatory reaction decreasing its intensity. During the period from the 3 to 15 days after the operation the signs of inflammatory reaction were observed in the mucous membrane, around the implant. The cartilage had’t almost changed. 30 days after the operation the implant sprouted with thin connective tissue fibers. The character of the inflammatory reaction tended to decrease. There were no signs of rejection. The cartilage didn’t reveal any signs of changes. The signs of the regeneration hypertrophy of the cartilage tissue appeared in the 30-60 days. By the 120th day after the operation a complete restoration of the nasal septum structure and germination of the implant with mature collagen fibers had completed. Thus one may conclude that the polyether complex fibers cloth gauze implant in the complex with the quadrangular cartilage can be used as an implant during the correction of the posttraumatic nasal septum deformations when there is deficiency of the autogenic cartilage. Porous implant structure contributes to its germination with connective tissue fibers increasing thus the nasal septum firmness. Besides the signs of the cartilage regeneration were revealed.

Keywords: nasal septum deformation, septoplasty, gauze implant, polyether fibers, cartilage regeneration
p. 45 - 54 of the original issue
References
  1. Богданов., В.В. Подслизистая резекция перегородки носа с имплантацией брефокости / В.В. Богданов., А. Г. Балабанцев // Материалы регион. науч. - практ. конф. оториноларингологов и расширенного пленума РНОЛО. - М., 1990.- С.62 - 63.
  2. Горбачевский, В. Н. Хирургические вмешательства при искривлении перегородки носа / В. Н. Горбачевский, В. Е. Макашев, И. В. Рушневский // Ж. ушных, носовых и горловых болезней. – 1992. - № 1. – С. 54 – 63.
  3. Дайхес, А.И. Пластическая хирургия в оториноларингологии в СССР / А.И. Дайхес // Вестн. оториноларингологии. - 1977. - №6. - С. 75 - 82.
  4. Кицера, А.Е. К вопросу о риносептопластике / А.Е. Кицера, А. А. Борисов // Вестн. оториноларингологии. - 1974. - № 4. - С. 31 - 34.
  5. Кицера, А.Е. Измерение и оценка дыхательной функции носа (ринопневмометрия) / А. Е. Кицера, А. А. Борисов, Ю. Г. Рыбачук // Вестн. оториноларингологии. - 1986. - № 2. - С. 78 - 81.
  6. 6. Кицера, А.Е. Методы функциональной и эстетической коррекции носового скелета. Сообщение II. Закрытая риносептоортопластика / А. Е. Кицера, А. А. Борисов // Журн. ушных, носовых и горловых болезней. - 1987. - №3. - С. 4 - 9.
  7. Курилин, И.А. Восстановление спинки носа и но совой перегородки при деформации протезами из тефлона / И. А. Курилин, Н. Ф. Федун // Журн. ушных, носовых и горловых болезней. - 1967. - № 1. - С. 25 - 30.
  8. Лопатин, А. С. Реконструктивная хирургия деформаций перегородки носа / А. С. Лопатин // Российская ринология. – 1994. – Прилож. №1. – С. 3 – 31.
  9. Стукер, Фред Дж. Структурная реконструкция при повторной ринопластике с использованием ушного хряща / Фред Дж. Стукер // Российская ринология. - 1994.- № 1.-С. 73.
  10. Bailey, B. Nasal septal surgery 1896-1899: transition and controversy / B. J. Bailey // Laryngoscope. – 1997. – Jan. Vol. 107, N. 1. – P. 10-60.
  11. Conley, J. Intranasal composite grafts for dorsal support / J. Conley // Arch. Otolaryngol. – 1985. – Vol. 111, N. 4. – P. 241-243.
  12. Hayward P. J. Fibrin glue in nasal septal surgery / P. J. Hayward, I. S. Mackay // J. Laryngol. Otol. – 1987. – Vol. 101, N. 2. – P. 133 – 138.
  13. Hellmich, S. Reconstruction of the destroyed septal infrastructure / S. Hellmich // Otolaryngol. Head Neck Surg. - 1989. – Vol. 100, № 2. – P. 133 -138.
  14. Endoscopic septoplasty: indications, technique, and results / P. H. Hwang [et al.] // Otolaryngol Head Neck Surg. – 1999. – May. - Vol. 120, N. 5. – P. 678-682
  15. Influence of Polydioxanone Foil on Growing Septal Cartilage After Surgery in an Animal Model / Boenisch Miriam [et al.] // Arch. Facial Plast Surg. – 2003. – N. 5. - P.316 - 319.
  16. Shultcz-Coulon, Н. J. Die Korrektur ausgepragter Deformitater des ventrokaudalen Septumabschnitts beim Kind / Н. J. Shultcz-Coulon // H. N. O. – 1989. - Bd 97, N. 4. – S. 123 – 127.
  17. Outcomes of septoplasty // N. S. Siegel [et al.] // Otolaryngol Head Neck Surg. – 2000. – Feb. - Vol. 122, N. 2. – P. 228- 232.
Contacts | ©Vitebsk State Medical University, 2007