Year 2008 Vol. 16 No 4

GENERAL AND SPECIAL SURGERY

EGOROV V.I., VISHNEVSKY V.A., KARMAZANOVSKY G.G., SCHYOGOLEV A.I., YASHINA N.I., PAVLOV K.A., DUBOVA E.A., MELEKHINA O.V., SHEVCHENKO T.V.

DIAGNOSTICS AND TREATMENT EXPERIENCE OF AUTOIMMUNE PANCREATITIS

The article presents the first in Russia experience of diagnostics and treatment of autoimmune pancreatitis and also some literature data about this pathology. The retrospective analysis of pathohistological preparations is carried out as well as of the case histories of 46 patients, who underwent during the period from 1994 till 2007 the pancreatoduodenal resection because of the pancreas cancer, which wasn’t confirmed at routine histological examination. In 37 cases the signs of chronic calculous and in 9 cases – of autoimmune pancreatitis were revealed on the basis of strict morphological criteria. In one observation the diagnosis of “autoimmune pancreatitis” was made on the basis of radiological and serologic criteria and it was also confirmed by an effective steroid therapy. Demographic, clinical and radiological features of autoimmune pancreatitis were studied as well as the immediate and distant results of the operative and conservative treatment.
The analysis of the obtained data has displayed that autoimmune pancreatitis has a certain clinical-instrumental manifestation that permits to suspect this disease after CT and MRT. However, comparative rarity of this disease and insufficient information about its manifestation limit the revelation possibilities of both diffusive and local forms of the disease and their adequate treatment consequently.

Keywords: autoimmune pancreatitis, chronic calculous pancreatitis, pancreas cancer, pancreatoduodenal resection
p. 9 – 18 of the original issue
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