Year 2019 Vol. 27 No 2

GENERAL & SPECIAL SURGERY

M.F. CHERKASOV, K.M. GALASHOKYAN, YA.M. STARTSEV, D.M. CHERKASOV, A.A. POMAZKOV, S.G. MELIKOVA

EFFECTS OF VACUUM THERAPY ON WOUND HEALING IN SACROCOCCYGEAL AREA

Rostov State Medical University, Rostov-on-Don,
The Russian Federation

Objective. To assess the wound repair in patients with pilonidal disease with open wound management and stimulation of healing by vacuum therapy.
Methods. The clinical study includes 73 patients who underwent open surgical treatment. There were 58 males (79.5%) and 15 females (20.5%). Patients were divided into the main group (n=39), where the original vacuum therapy after excision was carried out and the control group (n=34), where the excision of the pilonidal sinus was conducted with the open wound treatment by ointment bandage dressings. Clinical characteristics, cytological and planimetric parameters of healing were evaluated.
Results. In the main group, during the first week of treatment, a decrease in inflammation was observed, and by the second week – granulation tissue formation resulted in purification and epithelization of the wound, and by the third week the optimum conditions for wound contraction and scar tissue formation were observed. At cytological examination, from the 8th day after the VAC-therapy, inflammatory response decreased in 32 (82.1%) patients, from the 12th days regenerative cytological patterns were determined in 12 (30.8%) patients. By the 16th day in 23 (59%) observations of the main group the wound regenerative processes were noted, and in the control group, inflammatory-regenerative cytograms prevailed – 20 (58.8%). In the compared groups, it was found out that average healing and wound area reduction rate during the first 16 days of treatment was 2.6 times higher in main group.
Conclusions. Using VAC-therapy in postoperative wounds with open treatment of pilonidal disease promotes acceleration of healing and improves results of treatment in comparison with using standard bandage dressings.

Keywords: pilonidal sinus disease, surgical treatment, open wound healing, vacuum therapy, VAC-therapy, reparation
p. 153-160 of the original issue
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Address for correspondence:
344022, The Russian Federation,
Rostov-on-Don, Nakhichevansky Alley, 29,
Rostov State Medical University,
Department of Surgical Diseases.
Tel. +7 (918) 546 58 02,
e-mail: ya.carpusha88@yandex.ru,
Karapet M. Galashokyan
Information about the authors:
Cherkasov Mihail F., MD, Professor, Head of the Department of Surgical Diseases of the Faculty of Advanced Training and Retraining of Specialists, Rostov State Medical University, Rostov-on-Don, Russian Federation.
http://orcid.org/0000-0001-7587-8406
Galashokyan Karapet M., PhD, Assistant of the Department of Surgical Diseases of the Faculty of Advanced Training and Retraining of Specialists, Rostov State Medical University, Rostov-on-Don, Russian Federation.
https://orcid.org/0000-0001-5577-2436
Startsev Yury M., PhD, Associate Professor of the Department of Surgical Diseases of the Faculty of Advanced Training and Retraining of Specialists, Rostov State Medical University, Rostov-on-Don, Russian Federation.
http://orcid.org/0000-0002-5769-4598
Cherkasov Denis M., PhD, Associate Professor of the Department of Surgical Diseases №2, Rostov State Medical University, Rostov-on-Don, Russian Federation.
http://orcid.org/0000-0003-0320-7923
Pomazkov Andrey A., PhD, Associate Professor of the Department of Surgical Diseases of the Faculty of Advanced Training and Retraining of Specialists, Rostov State Medical University, Rostov-on-Don, Russian Federation.
https://orcid.org/0000-0001-6285-9556
Melikova Sabina G., Senior Laboratory Assistant of the Department of Surgical Diseases of the Faculty of Advanced Training and Retraining of Specialists, Rostov State Medical University, Rostov-on-Don, Russian Federation.
http://orcid.org/0000-0002-1966-1664
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