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Year 2021 Vol. 29 No 2

ANESTHESIOLOGY-REANIMATOLOGY

V.A. ZHIKHAREV 1, A.M. BOSTANOVA 1, A.S. BUSHUEV 1, V.A. KORYACHKIN 2, V.A. PORKHANOV 1

INTRAVENOUS INFUSIONS OF LIDOCAINE IN SURGERY OF THE TRACHEA

Research Institute - Krasnodar Regional Clinical Hospital No1 Named by Professor S. V. Ochapovsky 1, Krasnodar
Saint-Petersburg State Pediatric Medical University 2, Saint-Petersburg,
The Russian Federation

Objective. To evaluate the possibility of using intravenous infusion of lidocaine in tracheal surgery.
Methods. The analysis of case histories of patients (n=19) operated on for tracheal stenosis was carried out. Depending on the perioperative analgesia, the patients were divided into two groups: the 1st group (n=9) – intravenous infusion of lidocaine; the 2nd – (n = 10) – narcotic analgesics. Tracheal resection was carried out using the cervical access. Before tracheal transection and after tracheal anastomosis was applied, protective mechanical ventilation of the lungs was performed. The stage of tracheal resection and formation of anastomosis is high-frequency jet ventilation (HFJV). Anesthesia was maintained with sevoflurane, and after opening the tracheal lumen – with propofol 6-8 mg/kg/h. In the first group, an intravenous bolus of lidocaine 1.5 mg / kg was added to the induction, followed by a continuous infusion of 1.5 mg / kg / h during surgery. The concentration of lidocaine was determined 15 minutes after the bolus and 24 h after surgery. Hemodynamics, acid-base state, glycemia, response to the endotracheal tube, time of extubation, occurrence of postoperative nausea and vomiting were assessed. Pain syndrome was assessed using a visual analogue scale every 15 minutes for an hour, and then every 4 hours until the end of the first day, the consumption of opioids was recorded.
Results. Group 1 patients were extubated without agitation; the pressor response to extubation was less pronounced. Mean arterial pressure, blood gas composition and glycemia did not differ between these groups. There were no signs of systemic toxicity of lidocaine. Group 1 patients did not need promedol and tramadol, and the median and percentiles in group 2 patients, both for promedol and tramadol, were 60 [30; 60] and 400 [200; 400] mg, respectively. Four patients in group 2 had postoperative nausea and vomiting.
Conclusion. Intravenous infusion of lidocaineis considered to be an alternative to perioperative opioid analgesia in tracheal surgery performed from the cervical approach.

Keywords: intravenous infusion of lidocaine, thoracic surgery, tracheal surgery, tracheal stenosis, tracheal resection, postoperative analgesia, post-operative nausea and vomiting
p. 198-206 of the original issue
References
  1. Blasberg JD, Wright CD. Surgical considerations in tracheal and carinal resection. Semin Cardiothorac Vasc Anesth. 2012 Dec;16(4):190-95. doi: 10.1177/1089253212450342
  2. Hatipoglu Z, Turktan M, Avci A. The anesthesia of trachea and bronchus surgery. J Thorac Dis. 2016 Nov;8(11):3442-51. doi: 10.21037/jtd.2016.11.35
  3. Weibel S, Jelting Y, Pace NL, Helf A, Eberhart LH, Hahnenkamp K, Hollmann MW, Poepping DM, Schnabel A, Kranke P. Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults. Cochrane Database Syst Rev. 2018 Jun 4;6(6):CD009642. doi: 10.1002/14651858.CD009642.pub3
  4. Camilleri M, Lembo A, Katzka DA. Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits. Clin Gastroenterol Hepatol. 2017 Sep;15(9):1338-49. doi: 10.1016/j.cgh.2017.05.014
  5. Mehran RJ, Martin LW, Baker CM, Mena GE, Rice DC. Pain Management in an enhanced recovery pathway after thoracic surgical procedures. Ann Thorac Surg. 2016 Dec;102(6):e595-e596. doi: 10.1016/j.athoracsur.2016.05.050
  6. Zvara DA. Enhanced Recovery for thoracic surgery. Revista Mexicana de Anestesiología. 2017;40(Supl 1):S340-S344. https://www.medigraphic.com/pdfs/rma/cma-2017/cmas171ct.pdf
  7. Hayhurst CJ, Durieux ME. Differential Opioid Tolerance and Opioid-induced Hyperalgesia: A Clinical Reality. Anesthesiology. 2016 Feb;124(2):483-88. doi: 10.1097/ALN.0000000000000963
  8. Foldes FF, Molloy R, McNall PG, Koukal LR. Comparison of toxicity of intravenously given local anesthetic agents in man. J Am Med Assoc. 1960 Apr 2;172:1493-98. doi: 10.1001/jama.1960.03020140029007
  9. Bromage PR, Robson JG. Concentrations of lignocaine in the blood after intravenous, intramuscular epidural and endotracheal administration. Anaesthesia. 1961 Oct;16:461-78. doi: 10.1111/j.1365-2044.1961.tb13426.x
  10. Swenson BR, Gottschalk A, Wells LT, Rowlingson JC, Thompson PW, Barclay M, Sawyer RG, Friel CM, Foley E, Durieux ME. Intravenous lidocaine is as effective as epidural bupivacaine in reducing ileus duration, hospital stay, and pain after open colon resection: a randomized clinical trial. Reg Anesth Pain Med. 2010 Jul-Aug;35(4):370-76. doi: 10.1097/AAP.0b013e3181e8d5da
  11. Taniguchi T, Shibata K, Yamamoto K, Mizukoshi Y, Kobayashi T. Effects of lidocaine administration on hemodynamics and cytokine responses to endotoxemia in rabbits. Crit Care Med. 2000 Mar;28(3):755-59. doi: 10.1097/00003246-200003000-00025
  12. Truesdale K, Jurdi A. Nebulized lidocaine in the treatment of intractable cough. Am J Hosp Palliat Care. 2013 Sep;30(6):587-89. doi: 10.1177/1049909112458577
  13. Ahn E, Kang H, Choi GJ, Park YH, Yang SY, Kim BG, Choi SW. Intravenous lidocaine for effective pain relief after a laparoscopic colectomy: a prospective, randomized, double-blind, placebo-controlled study. Int Surg. 2015 Mar;100(3):394-401. doi: 10.9738/INTSURG-D-14-00225.1
  14. Kim TH, Kang H, Choi YS, Park JM, Chi KC, Shin HY, Hong JH. Pre- and intraoperative lidocaine injection for preemptive analgesics in laparoscopic gastrectomy: a prospective, randomized, double-blind, placebo-controlled study. J Laparoendosc Adv Surg Tech A. 2013 Aug;23(8):663-68. doi: 10.1089/lap.2012.0542
  15. Dungan K, Braithwaite SS, Preiser JC. Stress hyperglycemia. Lancet. 2009 May 23-29;373(Is 9677):1798-807. doi: 10.1016/S0140-6736 (09) 60553-5
  16. Kranke P, Jokinen J, Pace NL, Schnabel A, Hollmann MW, Hahnenkamp K, Eberhart LH, Poepping DM, Weibel S. Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery. Cochrane Database Syst Rev. 2015 Jul 16;(7):CD009642. doi: 10.1002/14651858.CD009642.pub2
  17. Terkawi AS, Tsang S, Kazemi A, Morton S, Luo R, Sanders DT, Regali LA, Columbano H, Kurtzeborn NY, Durieux ME. A clinical comparison of intravenous and epidural local local anesthetic for major abdominal surgery. Reg Anesth Pain Med. 2016 Jan-Feb;41(1):28-36. doi: 10.1097/AAP.0000000000000332
Address for correspondence:
350081, Russian Federation, Krasnodar,
1 May Str., 167 Research Institute-Regional Clinical Hospital No1 Named after Professor
S. V. Ochapovsky, the Department
of Anesthesiology and Resuscitation
tel. mob.:+7 903450-77-56
vasilii290873@yandex.ru
Zhikharev Vasilij A.
Information about the authors:
Zhikharev Vasilij A., PhD, Senior Clinical Intern, the Department of Anesthesiology and Resuscitation No1, Research Institute - Regional Clinical Hospital No1 Named after Professor S.V. Ochapovsky, Krasnodar, Russian Federation.
http://orcid.org/0000-0001-5147-5637
Bostanova Alina M., Clinical Intern, the Department of Anesthesiology and Resuscitation No1, Research Institute-Regional Clinical Hospital No1 named after Professor S.V. Ochapovsky, Krasnodar, Russian Federation.
http://orcid.org/0000-0002-2151-0611
Porkhanov Vladimir A., MD, Professor, Academician of RAS, Head Physician, Research Institute-Regional Clinical Hospital No1 Named after Professor S. V. Ochapovsky, Head of the Oncology Department with the Course of Thoracic Surgery of the Faculty of Advanced Training and Retraining of Specialists, Krasnodar, Russian Federation.
http://orcid.org/0000-0003-0572-1395
Koryachkin Viktor A., MD, Professor of the Department of Anesthesiology, Resuscitation and Urgent Pediatrics Department of Faculty of Postgraduate and Additional Professional Education, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russian Federation.
http://orcid.org/0000-0002-3400-8989
Bushuev Alexander S., Clinical Intern, the Department of Anesthesiology and Resuscitation, Research Institute-Regional Clinical Hospital No1 named after Professor S. V. Ochapovsky, Krasnodar, Russian Federation.
http://orcid.org/0000-0002-1427-4032
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