Novosti
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Year 2012 Vol. 20 No 4
ANESTHESIOLOGY-REANIMATOLOGY
S.A. TACHYLA
CHANGE OF ACID-BASE STATUS INDICATORS AND BLOOD GAS COMPOSITION AT CARRYING OUT BALANCED ENDOTRACHEAL ANESTHESIAIN THE ABDOMINAL SURGERY
ME “Mogilev Regional Hospital”
The Republic of Belarus
Objectives. To carry out a comparative assessment of the impact of a multi-component balanced endotracheal anesthesia with the use of isoflurane, sevoflurane and propofol on the parameters of acid-base status and gas composition of the venous blood in patients undergoing abdominal surgery.
Methods. 135 patients during anesthesia at abdominal surgeries were examined. Depending on the anesthetics used three groups were identified. In the first group (n=43) isoflurane was used to maintain a state of general anesthesia; in the second group (n=42) – sevoflurane, in the third group (n=50) – propofol. Venous blood samples obtained during anesthesia were collected for blood gas and of acid-base status analysis at six stages.
Results. Changes in acid-base status during anesthesia with different anesthetics are subjected to general regularities. During anesthesia a significant decrease in lactate levels and increase of pH to normal values were registered in comparison with the initial level. We have found out the partial pressure and oxygen saturation in the venous blood during anesthesia were significantly higher with inhaled anesthetics (isoflurane and sevoflurane in the mixture with nitrous oxide) use as compared with propofol.
Conclusions. We attribute the obtained changes in acid-base status to the appropriate carrying out of anesthesia and mechanical lung ventilation during the surgery. Significant increase of oxygen content in the venous blood during anesthesia maintenance is considered to repose in the organ protective effect basis of the inhaled anesthetics.
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212016, Respublika Belarus, Mogilev, ul. Belyinitskogo-Biruli, d. 12, UZ «Mogilevskaya oblastnaya bolnitsa», reanimatsionno-anesteziologicheskoe otdelenie,
е-mail: tsa80@inbox.ru,
Tochilo Sergey Anatolevich
Tochilo S.A., Anesthesiologist-Resuscitator of ME “Mogilev Regional Hospital”, Extramural post-graduate student oF the General and Clinical Pharmacology Chair with the Course of Anesthesiology and Resuscitation of EE “Gomel State Medical University”.
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