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Year 2015 Vol. 23 No 4

REVIEWS

T.K. VOLKOVICH

OCULAR SURFACE SQUAMOUS NEOPLASIA

SEE "Belarusian Medical Academy of Post-Graduate Education", Minsk
The Republic of Belarus

The article presents a scientific literature review devoted to studying the features of epidemiology, pathogenesis, diagnosis and treatment of ocular surface squamous neoplasia (OSSN). In different countries morbidity rate varies significantly from 0,03 to 3,5 cases per 100 000 population. The most important and studied causes of ocular surface neoplasia development are considered to be solar insolation, human papilloma virus, human immunodeficiency virus.
Variability of the clinical picture requires the proper differential diagnostics, since OSSN often masks as degenerative diseases of the conjunctiva (pinguecula, pterygium), vascularized corneal opacity, and can also manifest itself as melanoma or nevus.
Difficulties in the differential diagnostics based on clinical examination data necessitate the usage of high-tech research methods (optical coherence tomography of the ocular anterior segment) and the obligatory morphological diagnostics (cytological and histological diagnosis). Treatment of OSSN includes various medical and surgical approaches, more often their combination – surgical removal of tumors or usage of cytostatics or the medication interferon without taking into consideration the etiology. The high recurrence rate of OSSN is still remained – 10-56% of cases depending on the growth type, volume of surgery and duration of postoperative care of patients.
It is relevant to further studying the etiology and pathogenesis of ocular surface squamous neoplasia, as well as the development of integrated approaches in diagnosis and treatment taking into account the etiology of disease.

Keywords: cornea, conjunctiva, ocular surface, squamous neoplasia, neoplasm, morbidity rate, etiology of the disease
p. 460-466 of the original issue
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Address for correspondence:
220013, Respublika Belarus, g. Minsk,
ul. P. Brovki, d. 3, korp. 3,
GUO "Belorusskaya meditsinskaya akademiya
poslediplomnogo obrazovaniya",
kafedra oftalmologii,
tel. mob. 375 44 7949610,
e-mail: t.volkovich@rambler.ru,
Volkovich Tatyana Kazimirovna
Information about the authors:
Volkovich T.K. PhD, an associate professor of the ophthalmology chair of SEE "Belarusian Medical Academy of Post-graduate Education".
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