Novosti
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This journal is indexed in Scopus |
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Year 2015 Vol. 23 No 4
GENERAL & SPECIAL SURGERY
L.M. CHERNUKHA1, V.A. KHODOS 2, M.O. ARTEMENKO 1
THE ADVERSE EFFECTS OF SCLEROTHERAPY OF RETICULAR VEINS AND TELANGIECTASIAS
SE "National Institute of Surgery and Transplantology named after O.O. Shalimov", NAMS of Ukraine1
National Medical Academy of Post-Graduate Education named after P.L. Shupik2, Kiev
Ukraine
Objectives. To study the incidence of adverse effects in sclerotherapy of reticular veins and telangiectasia and to identify ways to optimize the method.
Methods. During the period 2009-2014 yrs. 223 women with reticular veins and telangiectasia of the lower limbs were subjected to treatment. The microfoam sclerotherapy was used in combination with liquid sclerotherapy in the first group (n=117, 52,47%) patients; the single liquid sclerotherapy was applied in the second group 9 (n=106, 47,53%). To perform microsclerotherapy Polidocanol and Lauromacrogol (0,5%, 1%) were used.
Results. The treatment results of patients in both groups were evaluated in 3, 6, 12 and 18 months. 3 months after sclerotherapy, skin hyperpigmentation was observed in all patients in the first group and in 92 (86,8%) patients in the second group (p<0,001). After 6 months hyperpigmentation disappeared in 35 (29,9%) patients in the first group and in 72 (67,9%) patients (p<0,001) in the second group. After 12 months the number of patients without skin hyperpigmentation in the first group increased up to 75 (64,1%), in the second group – up to 89 (83,9%) (p*<0,001). Skin hyperpigmentation in both groups in terms exceeding 12 months disappeared spontaneously up to 18 months. The number of patients with matting in the first group made up 32 (27,4%) compared with 14 (13,2%) – in the second group. After 6 months the ratio was the same – 25 (21,4%) compared with 12 (11,3%). After 12 months the spontaneous disappearance of matting was observed in both groups.
Conclusion. Microfoam application in combination with liquid sclerotherapy of reticular veins and telangiectasias is more economical than single liquid form, but is accompanied by significantly more side effects such as skin hyperpigmentation (p<0,001) and matting. The optimal technology of microsclerotherapy is considered to be a liquid sclerosant application in minimal concentrations.
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04112, Ukraine, Kiev,
ul. Dorgozhitskaya, d. 9,
Natsionalnaya meditsinskaya akademiya
poslediplomnogo obrazovaniya im.P.L. Shupika,
kafedra khirurgii i
sosudistoy khirurgii,
tel. mob.: 38 050 469-56-15,
e-mail: vkhodos@ukr.net,
Khodos Valentin Andreevich
Chernukha L.M. MD, a leading researcher of the department of the main vessels surgery of SE "National Institute of Surgery and Transplantology named after O.O. Shalimov" of NAMS of Ukraine, Kiev.
Khodos V.A. MD, an assistant of surgery and vascular surgery chair of "National Medical Academy of Post-graduate Education named after P.L. Shupik", Kiev.
Artemenki M.O. PhD, a researcher of the department of the main vessels surgery of SE "National Institute of Surgery and Transplantology named after O.O. Shalimov" of NAMS of Ukraine, Kiev.
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