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Khirurgii
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Year 2006 Vol. 14 No 3

SAMARA MOKHAMMAD ALI IBRAGIM

PECULIARITIES OF THE BLOOD LIPID PROFILE IN PATIENTS WITH PROSTATE BENIGN HYPERPLASIA

Prostate benign hyperplasia (PBH) is observed in approximately 20% males of 40 years of age, 70% males of 60 and 90% males of 80 and over. It was determined that the prostate is a hormone dependent organ. It is known that androgenic hormones are synthesized from cholesterol; besides cholesterol is actively used for cellular membrane formation, therefore blood lipid profile changes should be expected in PBH patients. 35 patients with stage I PBH, 40 patients with stage II PBH and 24 patients with stage III PBH were examined, 50 healthy males composed a control group. All the examined subjects were of the age of 485. The content of total cholesterol, triacylglycerol, low density lipoprotein (LDL) and high density lipoprotein (HDL) was determined in blood serum by means of fermentation, using standard chemical reagents sets. Stability and variability of lipid profile indices were estimated according to the entropy definition. It was determined that prostate benign hyperplasia develops on the background of hypercholesterolemia, hyperbetacholesterolemia of various stages, hypoalphacholesterolemia, normotriacylglycerolemia that is the evidence of a cholesterol reverse transport disturbance.

Keywords: prostate, benign hyperplasia, blood lipid profile, cholesterol transport
p. 51 - 55 of the original issue
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