Year 2007 Vol. 15 No 2

MODERN DIAGNOSTICS AND THERAPY

BLEDNOV A.V.

THE RESULTS OF CLINICAL DRESSING PREPARATIONS “COMBIXIN” AND “DIOSEPT” APPLICATION (CLINICAL PROBATION OF DRESSING PREPARATIONS)

Improvements of the results and shortening in treatment period of pyo-necrotic wounds remain rather actual surgical problem. The method of wounds treatment has been worked out, which is based on the application at the 1st and 2nd phases of wound process the preparation with immobilized forms of trypsin and dioxidin (Combixin); during the 2nd and 3rd phases – the preparation with immobilized form of dioxidin (Diosept). Clinical probation of wound-healing effects of the combined dressing preparations “Combixin” and “Diosept” has been performed to prove clinical efficiency of the given preparations in treatment of in-patients with pyo-inflammatory diseases. The testing has been performed using simple blind investigation with positive control in 40 patients. The groups with pyo-necrotic wounds and trophic ulcers have been singled out. High efficiency of new dressing preparations has been established in both groups. Acceleration of wound clearance and terms shortening of wound preparing to the plastic closure has also been 2-3 times more effective. Application of new preparations hasn’t been followed by any side effects.

Keywords: method of wounds and ulcers treatment, combined dressing preparations, inflammation phase reduction, proteolytic wounds clearance.
p. 90 - 97 of the original issue
References
  1. Кузин, М. И. Раны и раневая инфекция / М. И. Кузин, Б. М. Костюченок. – М.: Медицина, 1990. – С. 280-281.
  2. Парамонов, Б. А. Ожоги: руководство для врачей / Б. А. Парамонов, Я. О. Порембский, В. Г. Яблонский. – Спб.: СпецЛит, 2000. – 480 с.
  3. Бледнов, А. В. Разработка и применение иммобилизованных форм протеолитических ферментов в медицине / А. В. Бледнов // Вестник фармации. – 2005. – Т.27, N 1. – С.9-17.
  4. Бледнов, А. В. Перспективные направления в разработке новых перевязочных средств // Новости хирургии. – 2006. – Т. 14, № 1. – С. 9-19.
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