Novosti
Khirurgii
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indexed in Scopus



Year 2011 Vol. 19 No 3

LECTURES, REVIEWS

VINNIK YU.S., SALMINA A.B., DROBUSHEVSKAYA A.I., TEPLYAKOVA O.V., POGILENKOVA E.A., KOTIKOV A.R.

PATHOGENESIS PECULIARITIES OF LONG-HEALING WOUNDS

This review shows modern views on the molecular mechanisms of the main phases of normal and complicated wound healing process. Significance of functional capabilities of fibroblasts and keratinocytes has been shown as well as the properties of the extra cellular matrix, microbial contamination, cytokine and protease activation in the pathogenesis of chronic wound healing. Data concerning the role of the protein expression connexin in providing the processes of direct intercellular interaction at wound healing are presented.

Keywords: chronic wounds, fibroblasts, keratinocytes, connexins, cell growth factors
p. 101 110 of the original issue
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