Novosti
Khirurgii

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Year 2013 Vol. 21 No 2

REVIEWS

V.A. KOSINETS

NUTRITIONAL SUPPORT OF THE BODY IN CRITICAL CONDITIONS

SBEE HPE “IM Sechenov First Moscow State Medical University”
The Russian Federation

The literature analysis of pathologic changes in critical conditions and role of nutritional support in providing an organism with energetic and plastic substrates has been carried out. The hypoenergetic status is considered as the starting mechanism of «autocannibalism» processes that entail the subsequent decompensation of all systems of the body with the development of unfavorable outcomes. Nutritional support in critical conditions is of great importance. Pathological changes of metabolic processes testify to the appropriateness of combination of the preparations for enteral and parenteral nutrition together with the agents containing substrates for direct synthesis of macroergic compounds, in particular, the preparations of amber acid. It has been demonstrated that in generalized purulent peritonitis the preparations containing amber acid have a significant positive effect on processes of oxidative phosphorylation and ATP synthesis. Development of multilevel purposeful impact on links of biological oxidation will promote more effective and full-strength nutritive support of organism in the critical conditions.

Keywords: critical condition, peritonitis, nutritional support, parenteral nutrition, amber acid
p. 100 – 104 of the original issue
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Address for correspondence:
119991, Rossiyskaya Federatsiya, g. Moskva, ul. Yauzskaya, d. 11, GBOU VPO «Pervyiy Moskovskiy gosudarstvennyiy meditsinskiy universitet im. I.M. Sechenova», kafedra obschey khirurgii,
e-mail: vkosinets@yandex.ru,
Kosinets Vladimir Aleksandrovich
Information about the authors:
Kosinets V.A. PhD, an applicant for Doctor’s Degree of the General Surgery Chair of SBEE HPE “I.M. Sechenov First Moscow State Medical University”
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