Novosti
Khirurgii
This journal is
indexed in Scopus



Year 2018 Vol. 26 No 1

REVIEWS

DOI: https://dx.doi.org/10.18484/2305-0047.2018.1.72   |  

M.Y. GAIN, S.V. SHAKHRAI, Y.M. GAIN, D.V. KUDRYTSKI

LASER LIPOLYSIS: MECHANISMS, MODERN POSSIBILITIES AND USE PROSPECTS IN SURGERY

Belarusian Medical Academy of Post-Graduate Education, Minsk,
The Republic of Belarus

Objective. To estimate the prospects of surgical technologies of adipose tissue laser destruction by the analysis of literary data about the mechanisms, technical potential and areas of practical application.
Methods. Using the literature data, the comparative analysis of the main fields of application, mechanisms and efficiency of the modern laser lipolysis technologies was performed. The database of medical and biological publications PubMed (section biotechnology of National medical library of the USA) through NCBI-Entrez access was used. The analysis of more than 300 sources of medical literature was carried out.
Results. Laser lipolysis is the complex of surgical technologies aimed at thermal destruction of adipose tissue by laser radiation. Along the thermal destruction of adipocytes, use of the laser radiation of certain parameters effects collagen, promoting adipose cells destruction and skin lifting.
Diode laser lipolysis by the wavelength of 980 nanometers is characterized by less destructive action on the tissues and shorter rehabilitation period than traditional methods of liposuction. At present there are researches based on using the laser radiation of several sources of different power with various combinations of wavelength.
According to literature, the most widespread laser technologies of adipose tissue destruction are used for adipose tissue elimination by plastic and esthetic surgery, minimally-invasive excision of adipose tissue tumors (lipomas), and also for treatment of gynecomastia, hyperhidrosis, osmidrosis, cellulitis and some other conditions.
Conclusions. The literature analysis shows that numerous descriptions of laser lipolysis methods contain various, sometimes contradictory data on technology, efficiency, safety for a patient. Interest in this field is due to relevance of minimally-invasive technologies for correction of the most widespread surgical diseases in out-patient and short-term stays conditions.

Keywords: laser lipolysis, liposuction, lipoma, adipose tissue, minimally-invasive surgery
p. 72-81 of the original issue
References
  1. Apfelberg DB, Rosenthal S, Hunstad JP, Achauer B, Fodor PB. Progress report on multicenter study of laser-assisted liposuction. Aesthetic Plast Surg. 1994 Summer;18(3):259-64.
  2. Abdelaal MM, Aboelatta YA. Comparison of Blood Loss in Laser Lipolysis vs Traditional Liposuction. Aesthet Surg J. 2014 Aug;34(6):907-12. doi: 10.1177/1090820X14536904.
  3. Prado A, Andrades P, Danilla S, Leniz P, Castillo P, Gaete F. A prospective, randomized, double-blind, controlled clinical trial comparing laser-assisted lipoplasty with suction-assisted lipoplasty. Plast Reconstr Surg. 2006 Sep 15;118(4):1032-45. doi: 10.1097/01.prs.0000232428.37926.48.
  4. Leclère FM, Moreno-Moraga J, Mordon S, Servell P, Unglaub F, Kolb F, Rimareix F, Trelles MA. Laser-assisted lipolysis for cankle remodelling: a prospective study in 30 patients. Lasers Med Sci. 2014 Jan;29(1):131-36. doi: 10.1007/s10103-013-1279-4.
  5. Badin AZ, Gondek LB, Garcia MJ, Do Valle LCh, Flizikowski FB, De Noronha L. Analysis of laser lipolysis effects on human tissue samples obtained from liposuction. Aesthetic Plast Surg. 2005 Aug;29( Is 4):281-86. doi: 10.1007/s00266-004-0102-9.
  6. Goldman A, Wollina U, de Mundstock EC. Evaluation of Tissue Tightening by the Subdermal Nd: YAG Laser-Assisted Liposuction Versus Liposuction Alone. J Cutan Aesthet Surg. 2011 May;4(2):122-28. doi: 10.4103/0974-2077.85035.
  7. Goldman A, Schavelzon D, Blugerman G. Laser lipolysis:liposuction using Nd:YAG laser. Revista da Sociedade Brasileira de Cirurgia Plástica. 2002;17:17-26.
  8. Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Dermatol Surg Oncol. 1990 Mar;16(3):248-63.
  9. Mordon SR, Wassmer B, Reynaud JP, Zemmouri J. Mathematical modeling of laser lipolysis. Biomed Eng Online. 2008 Feb 29;7:10. doi: 10.1186/1475-925X-7-10.
  10. Woodhall KE, Saluja R, Khoury J, Goldman MP. A comparison of three separate clinical studies evaluating the safety and efficacy of laser-assisted lipolysis using 1,064, 1,320 nm, and a combined 1,064/1,320 nm multiplex device. Lasers Surg Med. 2009 Dec;41(10):774-78. doi: 10.1002/lsm.20859.
  11. Lim SD, Youn JI, Kim WS, Kim IH, Hwang TS, Han HS, Yeo UC. Comprehensive histologic analysis of interstitial lipolysis with the 1444 nm wavelength during a 3-month follow-up. Histol Histopathol. 2011 Nov;26(11):1375-82. doi: 10.14670/HH-26.1375.
  12. Sadick NS, Diktaban T, Smoller BR. New clinical outcomes utilizing a 1064-nm Nd:YAG laser for lipolysis of the torso oblique region. J Cosmet Laser Ther. 2010 Aug;12(4):170-75. doi: 10.3109/14764172.2010.502457.
  13. DiBernardo BE, Reyes J, Chen B. Evaluation of tissue thermal effects from 1064/1320-nm laser-assisted lipolysis and its clinical implications. J Cosmet Laser Ther. 2009 Jun;11(2):62-69. doi: 10.1016/j.asj.2009.08.06.
  14. Badin AZ, Moraes LM, Gondek L, Chiaratti MG, Canta L. Laser lipolysis: flaccidity under control. Aesthetic Plast Surg. 2002 Sep-Oct;26(5):335-39. doi: 10.1007/s00266-002-1510-3.
  15. Kim KH, Geronemus RG. Laser lipolysis using a novel 1,064 nm Nd:YAG Laser. Dermatol Surg. 2006 Feb;32(2):241-48; discussion 247.
  16. Mordon S, Eymard-Maurin AF, Wassmer B, Ringot J. Histologic evaluation of laser lipolysis: pulsed 1064-nm Nd:YAG laser versus cw 980-nm diode laser. Aesthet Surg J. 2007 May-Jun;27(3):263-68. doi: 10.1016/j.asj.2007.03.005.
  17. McBean JC, Katz BE. A pilot study of the efficacy of a 1,064 and 1,320 nm sequentially firing Nd:YAG laser device for lipolysis and skin tightening. Lasers Surg Med. 2009 Dec;41(10):779-84. doi: 10.1002/lsm.20858.
  18. Leclere FM, Alcolea JM, Vogt P, Moreno-Moraga J, Mordon S, Casoli V, Trelles MA. Laser-assisted lipolysis for arm contouring in Teimourian grades III and IV: A prospective study involving 22 patients. Plast Surg (Oakv). 2016; 24(1): 35-40. doi: 10.1007/s10103-014-1705-2.
  19. Goldman A. Submental Nd:Yag laser-assisted liposuction. Lasers Surg Med. 2006 Mar;38(3):181-84. doi: 10.1002/lsm.20270.
  20. Youn JI, Holcomb JD. Ablation efficiency and relative thermal confinement measurements using wavelengths 1,064, 1,320, and 1,444 nm for laser-assisted lipolysis. Lasers Med Sci. 2013 Feb;28(2):519-27. doi: 10.1007/s10103-012-1100-9.
  21. Licata G, Agostini T, Fanelli G, Grassetti L, Marcianò A, Rovatti PP, Pantaloni M, Zhang YX, Lazzeri D. Lipolysis using a new 1540-nm diode laser: a retrospective analysis of 230 consecutive procedures. J Cosmet Laser Ther. 2013 Aug;15(4):184-92. doi: 10.3109/14764172.2012.758382.
  22. Parlette EC, Kaminer ME. Laser-assisted liposuction: heres the skinny. Semin Cutan Med Surg. 2008 Dec;27(4):259-63. doi: 10.1016/j.sder.2008.09.002. Review.
  23. Khoury JG, Saluja R, Keel D, Detwiler S, Goldman MP. Histologic evaluation of interstitial lipolysis comparing a 1064, 1320 and 2100 nm laser in an ex vivo model. Lasers Surg Med. 2008 Aug;40(6):402-6. doi: 10.1002/lsm.20649.
  24. Levi JR, Veerappan A, Chen B, Mirkov M, Sierra R, Spiegel JH. Histologic evaluation of laser lipolysis comparing continuous wave vs pulsed lasers in an in vivo pig model. Arch Facial Plast Surg. 2011 Jan-Feb;13(1):41-50. doi: 10.1001/archfacial.2010.103.
  25. Leclère FM, Trelles M, Moreno-Moraga J, Servell P, Unglaub F, Mordon SR. 980-nm laser lipolysis (LAL): about 674 procedures in 359 patients. J Cosmet Laser Ther. 2012 Apr;14(2):67-73. doi: 10.3109/14764172.2012.670704.
  26. Seckel BR, Doherty ST, Childs JJ, Smirnov MZ, Cohen RH, Altshuler GB. The role of laser tunnels in laser-assisted lipolysis. Lasers Surg Med. 2009 Dec;41(Is 10):728-37. doi: 10.1002/lsm.20867.
  27. Valizadeh N, Jalaly NY, Zarghampour M, Barikbin B, Haghighatkhah HR. Evaluation of safety and efficacy of 980-nm diode laser-assisted lipolysis versus traditional liposuction for submental rejuvenation: a randomized clinical trial. J Cosmet Laser Ther. 2016;18(1):41-45. doi: org/10.3109/14764172.2015.1039041.
  28. Saluja R. Dual-wavelength laser lipolysis treatment of lipomas: a case report. J Drugs Dermatol. 2010 Apr;9(4):387-88.
  29. Stebbins WG, Hanke CW, Petersen J. Novel method of minimally invasive removal of large lipoma after laser lipolysis with 980 nm diode laser. Dermatol Ther. 2011 Jan-Feb;24(1):125-30. doi: 10.1111/j.1529-8019.2010.01385.x.
  30. Trelles MA, Mordon SR, Bonanad E, Moreno Moraga J, Heckmann A, Unglaub F, Betrouni N, Leclère FM. Laser-assisted lipolysis in the treatment of gynecomastia: a prospective study in 28 patients. Lasers Med Sci. 2013 Feb;28(2):375-82. doi: 10.1007/s10103-011-1043-6.
  31. Rho YK, Kim BJ, Kim MN, Kang KS, Han HJ. Laser lipolysis with pulsed 1064 nm Nd:YAG laser for the treatment of gynecomastia. Int J Dermatol. 2009 Dec;48(12):1353-59. doi: 10.1111/j.1365-4632.2009.04231.x.
  32. Lee SG, Ryu HJ, Kim IH. Minimally invasive surgery for axillary osmidrosis using a combination of subcutaneous tissue removal and a 1,444-nm Nd:YAG Laser. Ann Dermatol. 2014 Dec; 26(6): 755-57. Published online 2014 Nov 26. doi: 10.5021/ad.2014.26.6.755.
  33. Mordon SR, Trelles MA, Leclere FM, Betrouni N. New treatment techniques for axillary hyperhidrosis. J Cosmet Laser Ther. 2014 Oct;16(5):230-35. doi: 10.3109/14764172.2014.948883.
  34. Goldman A, Gotkin RH, Sarnoff DS, Prati C, Rossato F. Cellulite: a new treatment approach combining subdermal Nd:YAG laser lipolysis and autologous fat transplantation. Aesthet Surg J. 2008 Nov-Dec;28(6):656-62. doi: 10.1016/j.asj.2008.09.002.
Address for correspondence:
220013, The Republic of Belarus,
Minsk, P.Brovka Str., 3,
Belarusian Medical Academy
of Post-Graduate Education,
Emergent Surgery Department,
Tel. office: +375 17-225-88-10,
e-mail: mishahain@tut.by,
Gain Mikhail Y.
Information about the authors:
Gain Mikhail Y., PhD, Senior Lecturer of the Emergent Surgery Department, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
http://orcid.org/0000-0001-9012-5277
Shakhrai Siarhei V., MD, Associate Professor, Professor of the Emergent Surgery Department, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
http://orcid.org/0000-0002-9423-9535
Gain Yuri M., MD, Professor, Vice-Rector for Scientific Work, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
http://orcid.org/0000-0001-7622-5642
Kudrytski Dzmitry V., Post-Graduate Student of the Emergent Surgery Department, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
https://orcid.org/0000-0001-8581-2494
Contacts | ©Vitebsk State Medical University, 2007